Philadelphia 4, San Diego 0
Zack Wheeler struck out 10 over eight effective innings as the host Philadelphia Phillies posted a 4-0 win over the San Diego Padres on Monday.
Pittsburgh 7, St. Louis 0
Andrew Heaney and Chase Shugart combined on a four-hit shutout and the Pittsburgh Pirates offense remained hot during a 7-0 rout of the visiting St. Louis Cardinals on Monday night.
Toronto 5, NY Yankees 4
Vladimir Guerrero Jr. drove in three runs as the Toronto Blue Jays defeated the visiting New York Yankees 5-4 on Monday night in the opener of a four-game series.
Boston 13, Cincinnati 6
Wilyer Abreu made home run history and the Boston Red Sox scored seven runs in the first inning en route to a 13-6 victory over the visiting Cincinnati Reds on Monday night.
Athletics 6, Tampa Bay 4
Lawrence Butler lined a two-run, tiebreaking triple in the ninth inning as the Athletics opened a three-game series with a 6-4 victory over the host Tampa Bay Rays on Monday night.
Baltimore 10, Texas 6
Luis Vazquez, Ramon Laureano and Gunnar Henderson drove in runs in the 11th inning to lift the Baltimore Orioles to a wild 10-6 win over the Texas Rangers on Monday in the opener of a three-game series in Arlington, Texas.
Seattle 6, Kansas City 2
Randy Arozarena hit two homers and drove in four runs and Cal Raleigh went deep for the major-league-leading 33rd time this season as the Seattle Mariners defeated the visiting Kansas City Royals 6-2 on Monday.
Arizona 4, San Francisco 2
Alek Thomas had three hits and scored twice, including the go-ahead run on a Geraldo Perdomo single in the seventh inning, and the Arizona Diamondbacks defeated the San Francisco Giants 4-2 in the opener of a four-game series on Monday in Phoenix.